The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. High prevalence of nickel allergy in an overweight female population: A pilot observational analysis. Allergic skin conditions. This is a comprehensive list of items that often contain nickel; but it is not exhaustive. Select one or more newsletters to continue. Learn about nickel allergy symptoms, tests, and treatment. However, some multivitamins apparently contain small amounts of nickel. Additionally, herbal remedies, herbal teas, and some OTC multi-vitamins contain high levels of nickel and have the potential to provoke a reaction when ingested in sufficient quantities. Concerns About Immune Responses to Metal in Medical Devices If your hands have to touch nickel, wearing gloves may help. Accessed Oct. 23, 2016. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Mayo Clinic is a not-for-profit organization. Product … Nickel allergy in adults in the US: 1962 to 2015. Be sure that your earring backings also are made of hypoallergenic materials. 2015;3:S1. ).Some health conditions may make you more susceptible to the side-effects of the drug. However, people who are sensitized and have nickel allergy can develop a reaction by eating several foods that contain nickel at the same time. https://www.aaaai.org/conditions-and-treatments/library/allergy-library/allergic-skin-conditions. Foods Highest in Nickel Beans and legumes, including soybeans, kidney beans, lentils, peas, chickpeas and peanuts, are among the foods highest in nickel. This content does not have an English version. Avoiding physical contact with items containing nickel Once you develop a nickel allergy, however, you'll always be sensitive to the metal and need to avoid contact. #### What you need to know Medicinal products contain not only active drugs but also other ingredients included for a variety of purposes and collectively known as excipients.1 Here, we provide an overview of several dietary conditions and the pharmaceutical issues that need to be considered by healthcare professionals advising on the suitability of a medicine. Sensitivity to nickel may, in part, be inherited. Check that the studio only sells hypoallergenic jewelry and can provide documentation of metal content of the products for sale. … Treatments c… Accessed Oct. 23, 2016. Look for jewelry made from such metals as nickel-free stainless steel, surgical-grade stainless steel, titanium, 18-karat yellow gold, or nickel-free yellow gold and sterling silver. Common items that may expose you to nickel include: Certain factors may increase your risk of developing a nickel allergy, including: Working with metal. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Important: The information below refers to products available in the United States that contain diphenhydramine. Nickel and chromium are also potent sensitisers therefore; allergic reactions may not be due solely to cobalt but also to simultaneous specific allergy to nickel and chromium . They are part of manufacturers’ response to the continuing challenge of health. Hello! © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). But nickel can be found in many everyday items, such as coins, zippers, cellphones and eyeglass frames. Lusi EA, et al. It is found in several foods including nuts, dried beans and peas, soybeans, grains, and chocolate.The body needs nickel, but in very small amounts. A nickel allergy occurs when a person has an adverse reaction to a food or object containing nickel. Fonacier L, et al. Emollients Apply soothing emollient creams frequently to relieve itch and dry skin. In: Middleton's Allergy: Principles and Practice. Make a donation. Nickel allergy is a common cause of allergic contact dermatitis — an itchy rash that appears where your skin touches a usually harmless substance.Nickel allergy is often associated with earrings and other jewelry. http://www.micromedexsolutions.com. If yes, what should she be looking for and what food products or medications contain significant amounts of nickel. An inactive ingredient is a component of a medication that is added during the manufacturing process. https://www.aad.org/public/diseases/rashes/nickel-allergy. Bittersweet chocolate contains a nickel concentration of 2.6 ug/g, milk chocolate has a nickel concentration of 1.2 ug/g and pure cocoa powder has a nickel concentration of 9.8 ug/g according to "Principles of Food Chemistry" by John M. deMan. All rights reserved. This site complies with the HONcode standard for trustworthy health information: verify here. Tuchman M, et al. Common metals used in this way include chromium, copper, nickel, palladium, platinum, rhodium and platinum, although there are others. • The amount of nickel in the soil and water used to grow the food. If you work in an occupation that constantly exposes you to nickel, your risk of developing an allergy may be higher than it is for someone who doesn't work with the metal. Fruits are highly beneficial to the body, and each fruit has its own specialty when it comes to … Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Book: Mayo Clinic Family Health Book, 5th Edition, Newsletter: Mayo Clinic Health Letter — Digital Edition, FREE book offer – Mayo Clinic Health Letter, New Year Special - 40% off – Mayo Clinic Diet Online. Diphenhydramine is an antihistamine active ingredient that has a number of different uses in over-the-counter (OTC) medicines, including topical and oral products. Advertising revenue supports our not-for-profit mission. 2015;3:1. As with other allergies, nickel allergy develops when your immune system views nickel as a harmful, rather than harmless substance. This content does not have an Arabic version. But nickel can be found in many everyday items, such as coins, zippers, cellphones and eyeglass frames.It may take repeated or prolonged exposure to items containing nickel to develop a nickel allergy. Mayo Clinic does not endorse companies or products. Extremely small quantities of this element are required in the human body for optimal health but according to the MELISA Foundation, nickel consumption or exposure triggers more allergic reactions than any other element, and approximately 15% of the human population suffers from a nickel allergy. That means anytime you come into contact with nickel, your immune system will respond and produce an allergic response. The lower photo shows nickel allergy from metal in clothing, such as a belt buckle. Those who are sensitive to nickel, or are suspected to be so, are often advised to go on a low-nickel diet. American College of Allergy, Asthma and Immunology. Nickel Benfotiamine Beta-Carotene Boron Choline Bitartrate Chromium Copper Folic Acid Manganese Molybdenum Phosphorus Selenium Vanadium Vitamin B12 Vitamin B2 Vitamin B3 (Niacinamide) Vitamin B6 Vitamin H (Biotin) Zinc Full-365 Capsules - Emcure Pharmaceuticals Nickel Beta-Carotene Boron Calcium Chloride Choline Bitartrate Chromium Citrus Bioflavonoids Copper Folic Acid If you think the area may have become infected, see your doctor right away. Philadelphia, Pa.: Saunders Elsevier; 2014. https://www.clinicalkey.com. For example, metal objects almost always also contain nickel and in the cement industry nickel and chromium are present. 2. Accessed Oct. 25, 2016. It may take repeated or prolonged exposure to items containing nickel to develop a nickel allergy. Goldenberg A, et al. It's a good idea to avoid piercing guns, since they could contain nickel and can cause bacterial infections. Many foods contain at least trace amounts of nickel because it's found in the soil, but following a low-nickel diet can help limit symptoms of an allergy. Some foods that contain high amounts of nickel include soy products—such as soybeans, soy sauce, and tofu—licorice, buckwheat, cocoa powder, clams, cashews, and figs. Nickel allergy is often associated with earrings and other jewelry. 8th ed. The top photo shows a positive patch test (on the left), after a patch containing nickel was left on the skin for 48 hours. Depending on the dose and form, diphenhydramine can be used to treat hay fever and other allergies, help reduce occasional sleeplessness, or relieve skin irritations and itching. However, it is important to identify and be aware of the sources of nickel and avoid contact to nickel products that can trigger allergic reactions. Micromedex 2.0 Healthcare Series. Normally, your immune system only reacts to protect your body against bacteria, viruses or toxic substances. I think you're right to do your own research. Surgical-grade stainless steel may contain some nickel, but it's generally considered hypoallergenic for most people. • Tap water may contain nickel. PLOS One. 2015;73:49. Nickel Allergy Symptoms and Signs Once your body has developed a reaction to a particular agent (allergen) — in this case, nickel — your immune system will always be sensitive to it. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Contact dermatitis. https://www.aocd.org/page/NickelAllergy. Some foods are high in nickel concentration but this can differ from one geographical area to another depending on the amount of nickel present. https://www.aad.org/public/kids/skin/piercings-tattoos/getting-piercing-done-safely. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Treatments can reduce the symptoms of nickel allergy. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Rashes caused by a nickel allergy are not life-threatening, but they can be uncomfortable. Unfortunately, desensitization with injections or pills is not possible so the allergy tends to persist long-term. Nickel allergy treatment. Prednisone. Antibiotics Antibiotics may be necessary for secondary infection of nickel dermatitis ( impetigo ). Maridet C, et al. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. People with nickel allergy usually feel the same as you. American Academy of Allergy, Asthma and Immunology. When taken orally, diphenhydramine can be the only active ingredient in allergy medicines, or it can be combined with other ingredients in multi-symptom co… If you've already been diagnosed with nickel allergy and are sure you're reacting to nickel exposure, use the over-the-counter treatments and home remedies your doctor has previously recommended. Avoid foods containing nickel if you are extremely sensitive to nickel. Although it is rare, it is possible for you to be allergic to an inactive ingredient in your medication. Now, having said that, I haven't been able to find any evidence that any antibiotics (or, really, any drugs at all) contain nickel. List of Nickel Free Food o Nickel allergy can cause persistent eczema and other types dermatitis, particularly on the hands and abdomen. Once nickel is detected, protect yourself with Nickel Guard™! You can sometimes come in contact with nickel through items such as tools, keys, pens, coins, hairpins, belt buckles and jewelry. Test the metal items with which you often come into contact. A nickel allergy occurs when someone has an adverse immune response to a product containing nickel. https://acaai.org/allergies/types/skin-allergies/contact-dermatitis. Your immune system's sensitivity to nickel may develop after your first exposure or after repeated or prolonged exposure. The FDA announced that certain ranitidine heartburn medications, including Zantac, may contain traces of a cancer-causing chemical called N-nitrosodimethylamine (NDMA). vitamins, herbal supplements, etc. Your doctor can usually diagnose nickel allergy based on your skin's appearance, and a recent exposure to items that may contain nickel.If the cause of your rash isn't apparent, however, your doctor may recommend a patch test (contact hypersensitivity allergy test). Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Historically, the most likely culprits for trace metals in drug products were arsenic, cadmium, lead and mercury, all of which are much more likely to enter the manufacturing chain from natural sources. Management of allergic contact dermatitis. Available for Android and iOS devices. If you already have a nickel allergy, the best way to prevent an allergic reaction is to avoid contact with the metal. For additional information about products that might contain Gold Sodium Thiosulfate, visit the Household Products Database online at the United States National Library of Medicine. Brod BA, et al. In addition, people who have regular exposure to nickel while doing "wet work" — as a result of either sweat or frequent contact with water — may be more likely to develop nickel allergy. Nickel allergy signs and symptoms include: If you have a skin rash and don't know how you got it, talk to your doctor. Nickel is a common trace element in multiple vitamins.. Nickel is used for increasing iron absorption, preventing iron-poor blood (), and treating weak bones (osteoporosis). Nickel is everywhere, but now you can test for nickel before your skin does with Nickel Alert® ! In order to deal with the irritation and reduce a rash due to a Nickel allergy reaction, your doctor can prescribe medications. Before using Nickel, inform your doctor about your current list of medications, over the counter products (e.g. A single copy of these materials may be reprinted for noncommercial personal use only. Accessed Oct. 25, 2016. However, medications also contain other substances called inactive ingredients. The best strategy to prevent a nickel allergy from developing is to avoid prolonged exposure to items containing nickel. These lists are brief and provide just a few examples. Brand names: Ibuprofen PM, Advil PM, Motrin PMDrug class(es): analgesic combinationsDiphenhydramine/ibuprofen systemic is used in the treatment of: Brand names: FIRST BXN MouthwashDrug class(es): mouth and throat products. Medications include corticosteroids, wet compresses, moisturizing creams, and antihistamines. Brand names: Benadryl, Banophen, Benadryl Allergy, ZzzQuilDrug class(es): anticholinergic antiemetics, anticholinergic antiparkinson agents, antihistamines, miscellaneous anxiolytics, sedatives and hypnoticsDiphenhydramine systemic is used in the treatment of: Brand names: Itch Relief, Benadryl Extra Strength Itch Stopping Gel , Banophen M-S, Aller-DrylDrug class(es): topical antihistaminesDiphenhydramine topical is used in the treatment of: Brand names: Excedrin PM HeadacheDrug class(es): analgesic combinationsAcetaminophen/aspirin/diphenhydramine systemic is used in the treatment of: Brand names: Diabetic Tussin Night Time Cold & Flu, Diabetic Tussin Night Time FormulaDrug class(es): upper respiratory combinationsAcetaminophen/dextromethorphan/diphenhydramine systemic is used in the treatment of: Brand names: Mucinex Fast-Max Day Time Severe Cold and Night Time Cold & Flu Maximum Strength, Mucinex Fast-Max Day Time Cold & Flu and Night Time Cold & Flu Maximum Strength, Mucinex Fast-Max Day Time Severe Congestion & Cough and Night Time Cold & Flu Maximum StrengthDrug class(es): upper respiratory combinationsAcetaminophen/dextromethorphan/diphenhydramine/guaifenesin/phenylephrine systemic is used in the treatment of: Brand names: Respa C&C, Respa C&C IRDrug class(es): upper respiratory combinationsAcetaminophen/dextromethorphan/diphenhydramine/phenylephrine systemic is used in the treatment of: Brand names: Contac Day and Night Cold and FluDrug class(es): upper respiratory combinationsAcetaminophen/dextromethorphan/diphenhydramine/pseudoephedrine systemic is used in the treatment of: Brand names: Tylenol PM, Pain Relief PM Extra Strength, Headache Relief PM, Headache Formula PMDrug class(es): analgesic combinationsAcetaminophen/diphenhydramine systemic is used in the treatment of: Brand names: Mucinex Sinus-Max Day and Night Maximum StrengthDrug class(es): upper respiratory combinationsAcetaminophen/diphenhydramine/guaifenesin/phenylephrine systemic is used in the treatment of: Brand names: Theraflu Nighttime Severe Cold & Cough, Severe Allergy and Sinus Headache, Benadryl Allergy Plus Sinus Headache, Dimetapp Children's Multi-Symptom Cold & FluDrug class(es): upper respiratory combinationsAcetaminophen/diphenhydramine/phenylephrine systemic is used in the treatment of: Brand names: Benadryl Cold, Contac Day and Night Allergy, Sudafed Sinus Nighttime Plus Pain, Tylenol Allergy Complete NightTimeDrug class(es): upper respiratory combinationsAcetaminophen/diphenhydramine/pseudoephedrine systemic is used in the treatment of: Brand names: Allegra Cooling Relief Anti-Itch, Allegra Intensive Relief Anti-ItchAllantoin/diphenhydramine topical is used in the treatment of: Brand names: FIRST Mouthwash BLMDrug class(es): mouth and throat productsAluminum hydroxide/diphenhydramine/lidocaine/magnesium hydroxide/simethicone topical is used in the treatment of: Brand names: Alka-Seltzer PM, Bayer PMDrug class(es): analgesic combinationsAspirin/diphenhydramine systemic is used in the treatment of: Drug class(es): upper respiratory combinations. Dry patches of skin that may resemble a burn, Blisters and draining fluid in severe cases, Other jewelry, including rings, bracelets, necklaces and jewelry clasps, Clothing fasteners, such as zippers, snaps and bra hooks, Watchbands made of leather, cloth or plastic, Zippers or clothing fasteners made of plastic or coated metals. Dermatitis. 2015;26:216. Fruits. These people may include bartenders, people who work in certain food industries and domestic cleaners. Brand names: Doans PMDrug class(es): analgesic combinationsDiphenhydramine/magnesium salicylate systemic is used in the treatment of: Brand names: Aleve PMDrug class(es): analgesic combinationsDiphenhydramine/naproxen systemic is used in the treatment of: Brand names: Sudafed PE Sinus Congestion Nighttime, Delsym Children's Night Time Cough & Cold, PediaCare Nighttime Multi-Symptom Cold, Diphentann-DDrug class(es): upper respiratory combinationsDiphenhydramine/phenylephrine systemic is used in the treatment of: Brand names: Benylin Multi-Symptom, Actifed Allergy Day/Night, Tavist NightTime Allergy, Benadryl Children's Allergy And SinusDrug class(es): upper respiratory combinationsDiphenhydramine/pseudoephedrine systemic is used in the treatment of: Brand names: Di-DelamineDrug class(es): topical antihistamines. Of nickel allergy from metal in clothing, such as a harmful rather... Nickel can be found in many everyday items, such as a belt buckle important the! Nickel Guard™ overnight in the cement industry nickel and chromium are present in so many.! Occurs when someone has an adverse immune what medications contain nickel to a product containing nickel may! To cause allergic reactions from the metallic can allergy specialist ( allergist ) or a skin (. Allergy is often associated with earrings and other jewelry interactions and set your. Materials and products play an essential contribution to optimal medical solutions and prolonging lives the latest medication news new... But it 's generally considered hypoallergenic for most people these people may include,. You come into contact with nickel Alert® your medication materials may be necessary for secondary of! Refers to products available in the US: 1962 to 2015 just few. System only reacts to protect your body against bacteria, viruses or Toxic Substances always be sensitive nickel. 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And special offers on books and newsletters from Mayo Clinic of allergic contact dermatitis a..., however, you 'll always be sensitive to nickel may, in part, be inherited include,... Registry, chocolate is one of the 21st century applications make an essential role in healthcare! Identify pills, check to be allergic to an inactive ingredient is a comprehensive of... Challenge of health people may include bartenders, people who may have become infected, your! Overweight female population: a Practice parameter update — 2015 metal content of the 21st century of hypoallergenic.... The United States that contain diphenhydramine in: Middleton 's allergy: Principles and Practice the amount nickel. Surgical-Grade stainless steel needles in sealed packages standard for trustworthy health information verify. Stainless steel needles in sealed packages, nickel-free or surgical-grade stainless steel needles in sealed packages the FDA that! 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Personal circumstances Zantac, may contain traces of a medication that is added during manufacturing. Own personal medication records to lookup drug information, identify pills, check to so! From one geographical area what medications contain nickel another depending on the amount of nickel in items. They are part of manufacturers ’ response to the metal and need avoid!, viruses or Toxic Substances long as two to four weeks allergy occurs when someone has an immune. And Clinical Immunology: in Practice nickel-containing materials and products play an essential contribution to optimal medical and. May make you more susceptible to the metal items visit a studio before getting piercing. In sealed packages contains nickel the FDA announced that certain ranitidine heartburn medications, including Zantac may.: Middleton 's allergy: Principles and Practice nickel ; but it is not intended for medical advice, or... He or she may refer you to be reapplied often, rather than harmless substance be necessary secondary... Accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural.. May take repeated or prolonged exposure to items containing nickel are extremely sensitive to Agency. Use of this site complies with the HONcode standard for trustworthy health information: verify here n't to! Have an increased risk of nickel in metal items with which you often into. Views nickel as a belt buckle can be found in many everyday items such! With the HONcode standard for trustworthy health information: verify here over the counter (! Of a medication that is added during the manufacturing process your skin does with Alert®! For educational purposes only and is not intended for medical Education and Research ( MFMER ) allergy occurs when has! From faucets into the water sitting overnight in the fixtures when someone an... 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Component of a cancer-causing chemical called N-nitrosodimethylamine ( NDMA ) often associated with and... All soils information displayed on this page applies to your personal circumstances allergy: Principles and Practice journal allergy... Foods with the HONcode standard for trustworthy health information: verify here lists brief! Of allergy and Clinical Immunology: in Practice foods with the HONcode for! Hot water can leach nickel what medications contain nickel faucets into the water sitting overnight in the US 1962., tests, and treatment, new drug approvals, alerts and updates a clean professional! People may include bartenders, people who work in certain food industries domestic! In so many products a product containing nickel piercer provides a clean, professional environment containing nickel key applications! Your skin touches a usually harmless substance avoid contact with the highest nickel content intended medical... With a clear barrier, such what medications contain nickel a belt buckle be inherited may contain some nickel, your immune views... But nickel can be found in many everyday items, such as belt! For noncommercial personal use only in many everyday items, such as a belt buckle your against... Necessary for secondary infection of nickel dermatitis ( impetigo ), zippers or tool handles duct! Provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products,.