It is considered as a “reduced-risk” pesticide which replaces organophosphate pesticides. Before use, thoroughly agitate the spray mix until fully resuspended. The product is a slight eye and skin irritant and is a strong skin sensitiser. Br J Pharmacol 132, 587-595 PubMed. Copyright 2013 Awiner | All Rights Reserved, What Is Indoxacarb And How Does Indoxacarb Work. Lepidopteran insects represent the majority of pests on the indoxacarb label but it is also used to control many species of plant bugs, leafhoppers, fleahoppers, weevils, beetles, flies, cockroaches, and ants. Household products; Toxicity to humans Indoxacarb is an oxadiazine insecticide which targets lepidoptera, including beet armyworms, fire ants, and cockroaches. The reliable endpoints, appropriate for use in regulatory risk assessment, are presented. Lapied B, Grolleau F, Sattelle D B (2001) Indoxacarb, an oxadiazine insecticide, blocks insect neuronal sodium channels. It is also used as the active ingredient in Syngenta line of commercial pesticides: Advion and Arilon. A non-systemic, contact insecticide for use on a broad-spectrum of insect pests. For aggregate risk assessment, risk estimates resulting from food, drinking water, and residential uses are combined. Indoxacarb is a non-systemic insecticide. If unforeseen conditions prevent immediate use of the TITAN Indoxacarb 150 EC Insecticide spray mix, the mix may be stored up to 72 hours. Date Issued: October 30, 2000. Wear personal protective equipment. , Its main mode of action is via blocking of neuronal sodium channels. Avaunt insecticide is labeled for more than 100 crops and is effective against a broad spectrum of lepidopteran larvae such as cabbage looper, corn earworm, armyworm, peach twig borer and Oriental fruit moth as well as other difficult-to-control pests such as apple maggot, plum curculio, plant bugs and … Indoxacarb is a white powdered solid material formulated as a wettable granule and soluble concentrate. Indoxacarb and DCJW suppressed the peak amplitude of action potentials, and DCJW exhibited a faster time course and higher potency than … In addition, the existing Table 4 Animal Feed MRL of 3 mg/kg for grape pomace is adequate to account for residues in this commodity. Do not breathe vapours or spray mist. Usually,the insects will be dead after 24-60 hours.  Methemoglobinemia is a condition which ultimately decreases the effectiveness of red blood cells to exchange oxygen with organs. Apply Advion WDG using a coarse low-pressure spray as a spot or crack and crevice treatment to infested areas or areas suspected to be infested. United States Environmental Protection Agency. Provide adequate ventilation. The effects of the oxadiazine insecticide indoxacarb and its N-decarbomethoxylated metabolite (DCJW) on tetrodotoxin-resistant (TTX-R) voltage-gated sodium channels in rat dorsal ganglion neurons were studied using the whole-cell patch clamp technique. The effectiveness of Steward EC on resistant individuals could be significantly reduced. Br J Pharmacol 132 (2), 587-595 PubMed. It is fairly lipophilic with a Kow of 4.65. Indoxacarb is a pesticide that is used to kill lepidopteran larvae such as butterflies and moths. Because of its chemical structure is complex, which contains indane, so we called it indoxacarb. It is also used as the active ingredient in Syngenta line of commercial pesticides: Advion and Arilon. 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